All in all, did Anatole’s tamperings make things better or worse?
I guess that depends on the purpose. Those receiving treatment and got better would consider Anatole’s tampering worthwhile. Anatatole’‘s tampering with both Pito’s and Tullia’s potions were effective in many ways. Their usage deceived others and saved both individuals’ lives. According to Anatole his experiments laid the groundwork to future scientific discoveries. Sure, he couldn’t turn sand into gold but he did increase Luigi’s lifespan.